This study examines how photoreceptor degeneration progresses in rd10 mice, a model of retinitis pigmentosa. At an early degenerative stage, the full breadth of retinal output is still present, despite disease progression, though distinct retinal ganglion cell types show varying degrees of response to photoreceptor loss.

Dyszkant, N., Oesterle, J., Qiu, Y., Harrer, M., Schubert, T., Gonschorek, D., Euler, T. (2025). Photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types. The Journal of Physiology, 603(21), 6599–6621. https://doi.org/10.1113/JP287643

§ shared senior authorship

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